The Venture Bros. is one of those shows that seems really weird based on any previews or short clips you may have seen, but it actually has some of the best writing I have ever seen in a show, especially when it comes to minority characters. In the show, Brock Samson is a bodyguard and agent working for the OSI or Office of Secret Intelligence. He was first trained by Colonel Hunter Gathers, his mentor, and a man he says was like a father to him. Hunter also might be transgender.
(The pronouns Hunter is addressed as changes based on his biological sex in the show. Since Hunter is currently a male on the show I will refer to him with male pronouns.)